In France, medicines are packaged and distributed to the public in boxes containing several doses, unlike in other countries, particularly in Europe, where they are dispensed by unit dose, i.e. in quantities strictly equal to those prescribed. The box has the advantage of protecting the product, guaranteeing its authenticity by means of a so-called serialisation code, and acts as a medium for information such as precautions for use. The entire pharmaceutical chain in France, from drugs manufacturing to its distribution between pharmacies and to the patient, relies on a system based on the box, including stock management and pricing software of community pharmacies. According to the prescription, the pharmacist must dispense the minimum number of boxes required to cover the duration of the treatment, with potentially some excess. The leftovers may be misused later on through self-medication, or stocked and then destroyed, with all the resulting damage in financial, health and environmental terms. Dispensing by unit dose may therefore be a way of addressing this wastage. The purpose of this report is to examine its relevance and feasibility.